Perkin Elmer LAMBDA 365+ UV/Vis Spectrometer
Associated Analytical Procedures
Context in Practice: Example Specifications
From: Typical mRNA (Drug Substance) Specifications
This instrument is used in the context of measuring the Quality Attribute mRNA Concentration (Total) with the following details:
- Purpose / Rationale: Quantifies total nucleic acid content for formulation calculations and dose preparation
- Typical Acceptance Criteria: 90–110% of target concentration (e.g., 0.9–1.1 mg/mL for 1.0 mg/mL target) ; Established based on process capability and clinical dose requirements