Maurice CE-SDS and icIEF Instrument

The Maurice System is an automated capillary electrophoresis platform that integrates iCIEF (imaged capillary isoelectric focusing) and CE-SDS (capillary gel electrophoresis) within a single instrument. It enables charge-variant and size-based analysis of biologics—including monoclonal antibodies, fusion proteins, and gene-therapy capsid proteins—under fully automated, cartridge-based operation.

The system replaces traditional slab gels and manual IEF workflows, providing quantitative, high-resolution separations with minimal hands-on time. Its design supports method transferability across sites and phases, aligning with modern Analytical Procedure Lifecycle (APL) principles.

Typical Use Cases
Charge heterogeneity (iCIEF) for monoclonal antibodies or recombinant proteins

Purity and identity (CE-SDS) of viral capsid or plasmid-encoded proteins

Comparability and stability studies under GMP environments