PA 800 Plus System (SCIEX)
Associated Analytical Procedures
Context in Practice: Example Specifications
From: Typical AAV Drug Product Specifications
This instrument is used in the context of measuring the Quality Attribute Capsid Charge Heterogeneity with the following details:
- Purpose / Rationale: Monitors PTMs and ensures a consistent charge profile, which impacts tropism and stability.
- Typical Acceptance Criteria: Charge profile comparable to reference within preset criteria (main/variant peaks, apparent pI).